Comprehensive HBOT Research: Exploring the Science Behind Hyperbaric Oxygen Therapy

Discover the Latest Studies and Timeless Insights on the

Benefits of Hyperbaric Oxygen Therapy (HBOT)"

Research Supporting Hyperbaric Oxygen Therapy (HBOT)

At HBOT Revolution, we are committed to providing the most comprehensive and up-to-date information on the benefits of Hyperbaric Oxygen Therapy (HBOT). Our curated database of studies highlights the diverse applications of HBOT, ranging from improving brain metabolism and treating cerebral palsy to addressing autoimmune inflammation and neurological recovery. While some of the studies on our website date back over 20 years, they continue to provide foundational insights into the mechanisms and efficacy of HBOT. As new research emerges, we are dedicated to updating this section to reflect the latest advancements in the field.

Whether you are exploring HBOT for its anti-inflammatory properties, neuroprotective benefits, or potential for enhancing recovery in conditions like cerebral palsy or stroke, this resource offers scientifically backed information to support your journey. Explore how HBOT is transforming health outcomes and discover how ongoing research continues to expand its applications.

Visit us often to stay informed about the newest studies and evidence in HBOT's revolutionary impact on wellness and recovery.

HBOT Mechanism

Bhutani S, Vishwanath G. "Hyperbaric oxygen and wound healing." Indian Journal of Plastic Surgery. 2012;45(2):316–324. doi:10.4103/0970-0358.101309. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490679/

Thom SR. "Hyperbaric oxygen: its mechanisms and efficacy." Plastic and Reconstructive Surgery. 2011;127(Suppl 1):131S–141S. doi:10.1097/PRS.0b013e3181fbe2bf.

Link: https://journals.lww.com/plasreconsurg/fulltext/2011/01001/hyperbaric_oxygen__its_mechanisms_and_efficacy.23.aspx

Thom SR. "Oxidative stress is fundamental to hyperbaric oxygen therapy." Journal of Applied Physiology (1985). 2009;106(3):988–995. doi:10.1152/japplphysiol.91004.2008. Link: https://journals.physiology.org/doi/full/10.1152/japplphysiol.91004.2008

Wingelaar TT, Brinkman P, van Ooij PJAM, et al. "Markers of Pulmonary Oxygen Toxicity in Hyperbaric Oxygen Therapy Using Exhaled Breath Analysis." Frontiers in Physiology. 2019;10:475. Published 2019 Apr 24. doi:10.3389/fphys.2019.00475.

Link: https://www.frontiersin.org/articles/10.3389/fphys.2019.00475/fullGill

AL, Bell CNA. "Hyperbaric oxygen: its uses, mechanisms of action and outcomes." QJM: An International Journal of Medicine. 2004;97(7):385–395. doi:10.1093/qjmed/hch074.

Link: https://academic.oup.com/qjmed/article/97/7/385/1567601

HBOT and General Health

Fife CE, Eckert KA, Carter MJ. "An update on the appropriate role for hyperbaric oxygen: indications and evidence." Plastic and Reconstructive Surgery. 2016;138(3 Suppl):107S–116S. doi:10.1097/PRS.0000000000002714.

Link: https://journals.lww.com/plasreconsurg/Fulltext/2016/09001/An_Update_on_the_Appropriate_Role_for_Hyperbaric.15.aspx

Thom SR. "Oxidative stress is fundamental to hyperbaric oxygen therapy." Journal of Applied Physiology (1985). 2009;106(3):988–995. doi:10.1152/japplphysiol.91004.2008.

Link: https://journals.physiology.org/doi/full/10.1152/japplphysiol.91004.2008

Fujita N, Ono M, Tomioka T, et al. "Effects of hyperbaric oxygen at 1.25 atmospheres absolute with normal air on macrophage number and infiltration during rat skeletal muscle regeneration." PLoS One. 2014;9(12). Published 2014 Dec 22. doi:10.1371/journal.pone.0115685.

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115685

Vadas D, Kalichman L, Hadanny A, et al. "Hyperbaric oxygen environment can enhance brain activity and multitasking performance." Frontiers in Integrative Neuroscience. 2017;11:25. Published 2017 Sep 27. doi:10.3389/fnint.2017.00025.

Link: https://www.frontiersin.org/articles/10.3389/fnint.2017.00025/full

Hink J, Jansen E. "Are superoxide and/or hydrogen peroxide responsible for some of the beneficial effects of hyperbaric oxygen therapy?" Medical Hypotheses. 2001;57(6):764–769.

Link: https://pubmed.ncbi.nlm.nih.gov/11747881/

HBOT and Dementia/Alzheimer’s

Harch PG, Fogarty EF. "Hyperbaric oxygen therapy for Alzheimer’s dementia with positron emission tomography imaging: a case report." Medical Gas Research. 2019;8(4):181–184. Published 2019 Jan 9. doi:10.4103/2045-9912.248271.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347177/

Shapira R, Efrati S, Ashery U. "Hyperbaric oxygen therapy as a new approach for Alzheimer’s disease." Neural Regeneration Research. 2018;13(5):817–818. doi:10.4103/1673-5374.232475.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953028/

Qiang L, Lan X, Su-qin X, et al. "Meta-Analysis on the Efficacy and Safety of Hyperbaric Oxygen as Adjunctive Therapy for Vascular Dementia." Frontiers in Aging Neuroscience. 2019;11:86. doi:10.3389/fnagi.2019.00086.

Link: https://www.frontiersin.org/articles/10.3389/fnagi.2019.00086/full

HBOT and Fibromyalgia

Efrati S, Golan H, Bechor Y, et al. "Hyperbaric oxygen therapy can diminish fibromyalgia syndrome–prospective clinical trial." PLoS One. 2015;10(5). Published 2015 May 26. doi:10.1371/journal.pone.0127012.

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127012

Hadanny A, Bechor Y, Catalogna M, et al. "Hyperbaric oxygen therapy can induce neuroplasticity and significant clinical improvement in patients suffering from fibromyalgia with a history of childhood sexual abuse–randomized controlled trial." Frontiers in Psychology. 2018;9:2495. doi:10.3389/fpsyg.2018.02495.

Link: https://www.frontiersin.org/articles/10.3389/fpsyg.2018.02495/full

Efrati S, Hadanny A, Daphna-Tekoah S, et al. "Recovery of repressed memories in fibromyalgia patients managed with hyperbaric oxygen–case series presentation and suggested bio-psycho-social mechanism." Frontiers in Psychology. 2018;9:848. doi:10.3389/fpsyg.2018.00848.

Link: https://www.frontiersin.org/articles/10.3389/fpsyg.2018.00848/full

Yildiz S, Kiralp MZ, Akin A, et al. "A new modality for fibromyalgia syndrome: hyperbaric oxygen therapy." Journal of International Medical Research. 2004;32(3):263-267.

Link: https://journals.sagepub.com/doi/10.1177/147323000403200313

HBOT and Autism

Rossignol DA, Bradstreet JJ, Van Dyke K, et al. "Hyperbaric oxygen in autism spectrum disorders." Medical Gas Research. 2012;2(1):16. doi:10.1186/2045-9912-2-16.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447607/

Rossignol DA, Rossignol LW, Smith S, et al. "Hyperbaric for children with autism: a multicenter, randomized, double-blind, controlled trial." BMC Pediatrics. 2009;9:21. doi:10.1186/1471-2431-9-21.

Link: https://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-9-21

Xiong T, Chen H, Luo R, et al. "Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD)." Cochrane Database of Systematic Reviews. 2016;10. doi:10.1002/14651858.CD010922.pub2.

Link: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010922.pub2/full

Rossignol DA, Rossignol LW. "Hyperbaric oxygen therapy may improve symptoms in autistic children." Medical Hypotheses. 2006;67(2):216-228. doi:10.1016/j.mehy.2006.02.009.

Link: https://www.sciencedirect.com/science/article/abs/pii/S0306987706001181

Rossignol DA, Frye RE. "Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism." Frontiers in Physiology. 2014;5:150. doi:10.3389/fphys.2014.00150.

Link: https://www.frontiersin.org/articles/10.3389/fphys.2014.00150/full

HBOT and Infection

Çimşit M, Uzun G, Yıldız S. "Hyperbaric oxygen therapy as an anti-infective agent." Expert Review of Anti-infective Therapy. 2009;7(8):1015-1026. doi:10.1586/eri.09.76.

Link: https://www.tandfonline.com/doi/full/10.1586/eri.09.76

Ezra N, Dang K, Heuser G. "Improvement of attention span and reaction time with hyperbaric oxygen in patients with toxic injury due to mold exposure." European Journal of Clinical Microbiology & Infectious Diseases. 2011;30(1):1–6. doi:10.1007/s10096-010-0937-8.

Link: https://link.springer.com/article/10.1007/s10096-010-0937-8

Mader JT, Brown GL, Guckian JC, et al. "A mechanism for the amelioration by hyperbaric oxygen of experimental staphylococcal osteomyelitis in rabbits." Journal of Infectious Diseases. 1980;142(6):915-922.Link: https://academic.oup.com/jid/article-abstract/142/6/915/2192487

Delasotta LA, Hanflik A, Bicking G, et al. "Hyperbaric oxygen for osteomyelitis in a compromised host." Open Orthopaedics Journal. 2013;7:114–117. doi:10.2174/1874325001307010114.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688397/

Ciofu O, Tolker-Nielsen T. "Tolerance and resistance of Pseudomonas aeruginosa biofilms to antimicrobial agents–how P. aeruginosa can escape antibiotics." Frontiers in Microbiology. 2019;10:913. doi:10.3389/fmicb.2019.00913.

Link: https://www.frontiersin.org/articles/10.3389/fmicb.2019.00913/full

Kolpen M, Lerche CJ, Kragh KN, et al. "Hyperbaric oxygen sensitizes anoxic pseudomonas aeruginosa biofilm to ciprofloxacin." Antimicrobial Agents and Chemotherapy. 2017;61(11). doi:10.1128/AAC.01024-17.

Link: https://journals.asm.org/doi/full/10.1128/AAC.01024-17

Gade PAV, Olsen TB, Jensen PØ, et al. "Modeling of ciprofloxacin killing enhanced by hyperbaric oxygen in Pseudomonas aeruginosa PAO1 biofilms." PLoS One. 2018;13(6). doi:10.1371/journal.pone.0198909.

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198909

Memar MY, Yekani M, Alizadeh N, et al. "Hyperbaric oxygen therapy: antimicrobial mechanisms and clinical application for infections." Biomedicine & Pharmacotherapy. 2019;109:440-447. doi:10.1016/j.biopha.2018.10.142.

Link: https://www.sciencedirect.com/science/article/abs/pii/S0753332218310296

Kaye D. "Effect of hyperbaric oxygen on Clostridia in vitro and in vivo." Proceedings of the Society for Experimental Biology and Medicine. 1967;124:360.Link: https://journals.sagepub.com/doi/10.3181/00379727-124-31795

HBOT and Cancer (Including Keto)

İyikesici M, Slocum A, Slocum A, et al. "Efficacy of metabolically supported chemotherapy combined with ketogenic diet, hyperthermia, and hyperbaric oxygen therapy for stage IV triple-negative breast cancer." Cureus. 2017;9(7). doi:10.7759/cureus.1445.

Link: https://www.cureus.com/articles/7542

Poff AM, Ari C, Seyfried TN, et al. "The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer." PLoS One. 2013;8(6). doi:10.1371/journal.pone.0065522.Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065522

Seyfried TN, Mukherjee P. "The metabolic link between cancer and nutrition." Nutrition and Metabolism. 2005;2:30. doi:10.1186/1743-7075-2-30.Link: https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-30

Vander Heiden MG, Cantley LC, Thompson CB. "Understanding the Warburg effect: the metabolic requirements of cell proliferation." Science. 2009;324(5930):1029–1033. doi:10.1126/science.1160809.Link: https://www.science.org/doi/full/10.1126/science.1160809

Cancer (HBOT Only)

Moen I, Stuhr LE. "Hyperbaric oxygen therapy and cancer: a review." Target Oncology. 2012;7(4):233–242. doi:10.1007/s11523-012-0233-x.Link: https://link.springer.com/article/10.1007/s11523-012-0233-x

Thom SR, Bhopale VM, Yang M. "Microparticle-induced vascular injury in mice following decompression is inhibited by hyperbaric oxygen: effects on microparticles and interleukin-1." Journal of Applied Physiology. 2019;126(4):1093–1100.Link: https://journals.physiology.org/doi/full/10.1152/japplphysiol.00909.2018

Niezgoda JA, Serena TE, Carter MJ. "Outcomes of radiation injuries using hyperbaric oxygen therapy: an observational cohort study." Advances in Skin & Wound Care. 2016;29(1):12-19.Link: https://journals.lww.com/aswcjournal/Abstract/2016/01000/Outcomes_of_Radiation_Injuries_Using_Hyperbaric.5.aspx

Stepień K, Ostrowski RP, Matyja E. "Hyperbaric oxygen as an adjunctive therapy in the management of malignancies, including brain tumors." Medical Oncology. 2016;33(9):101. doi:10.1007/s12032-016-0814-0.Link: https://link.springer.com/article/10.1007/s12032-016-0814-0

Oscarsson N, Ny L, Mölne J, et al. "Hyperbaric oxygen reverses radiation-induced pro-fibrotic and oxidative stress responses in a rat model." Free Radical Biology and Medicine. 2017;103:248–255. doi:10.1016/j.freeradbiomed.2016.12.030.Link: https://www.sciencedirect.com/science/article/abs/pii/S0891584916311065

Zembrzuska K, Ostrowski RP, Matyja E. "Hyperbaric oxygen increases glioma cell sensitivity to antitumor drugs with a novel isothiourea derivative in vitro." Oncology Reports. 2019;41(5):2703–2716. doi:10.3892/or.2019.7064.Link: https://www.spandidos-publications.com/10.3892/or.2019.7064

Lu QZ, Li X, Ouyang J, et al. "Further application of hyperbaric oxygen in prostate cancer." Medical Gas Research. 2019;8(4):167–171. Published 2019 Jan 9. doi:10.4103/2045-9912.248268.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347175/

Choudhury R. "Hypoxia and hyperbaric oxygen therapy: a review." International Journal of General Medicine. 2018;11:431–442. Published 2018 Nov 20. doi:10.2147/IJGM.S172460.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248342/

HBOT and Wound Healing

Health Quality Ontario. "Hyperbaric oxygen therapy for the management of diabetic foot ulcers: a health technology assessment." Ontario Health Technology Assessment Series. 2017;17(5):1–142.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461900/

Hou S, Wu G, Liang J, et al. "Hyperbaric oxygen on rehabilitation of brain tumors after surgery and effects on TNF-α and IL-6 levels." Oncology Letters. 2019;17(3):3277–3282. doi:10.3892/ol.2019.10000.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394675/

Perren S, Gatt A, Papanas N, et al. "Hyperbaric oxygen therapy in ischemic foot ulcers in type 2 diabetes: a clinical trial." Open Cardiovascular Medicine Journal. 2018;12:80–85. Published 2018 Aug 31. doi:10.2174/1874192401812010080.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135494/

Eskes AM, Ubbink DT, Lubbers MJ, et al. "Hyperbaric oxygen therapy: solution for difficult-to-heal acute wounds? Systematic review." World Journal of Surgery. 2011;35(3):535–542. doi:10.1007/s00268-010-0923-4.

Link: https://link.springer.com/article/10.1007/s00268-010-0923-4

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The Science Behind

Hyperbaric Therapy

Learn More

The Science Behind

Hyperbaric Therapy

Why Should You Consider Hyperbaric Oxygen Therapy?

Hyperbaric Oxygen Therapy (HBOT) represents an advanced, evidence-backed treatment modality that can significantly enhance the service offerings in your practice.

For those on the cutting edge of wellness, embracing biohacking practices and the pursuit of optimal health, Hyperbaric Oxygen Therapy (HBOT) offers a scientifically grounded and potent modality to consider. Incorporating HBOT into your biohacking regimen can elevate your health optimization strategies and unlock new wellness potential.

Being non-invasive and having extensive support for its effectiveness, HBOT is an appealing addition for any health-focused individual.

Value-Driven, Portable Hyperbaric Chambers

We have revolutionized the wellness field with our pioneering approach to hyperbaric therapy. From our earliest days, our commitment has been to deliver exceptionally safe, high-quality, and conveniently portable hyperbaric chambers to physicians, elite athletes, wellness centers, and families.

Our chambers empower users with the ability to self-administer treatment, ushering in a new era of hyperbaric technology.

We've thoughtfully designed our portable range to offer not just simplicity and convenience, but also the best value for your investment. These cost-effective chambers provide impactful therapy that has benefited hundreds of thousands of people globally.

You're investing in a product that combines affordability with top-tier therapeutic technology.

Best Hyperbaric Oxygen Therapy Chambers (HBOT)

Welcome to HBOT Planet, your trusted partner for state-of-the-art Hyperbaric Oxygen Therapy (HBOT) chambers designed to help you achieve optimal health and wellness.

Experience

Nuestro primer objetivo es ayudarlo a aliviar su dolor e incomodidad lo antes posible.

Safety

Our chambers are the preferred choice for an increasing number of doctors, elite athletes, and households for their recovery needs. Our confidence stems from our commitment to ensuring each chamber we distribute achieves the industry's top safety ratings.

Customer Support

El cuidado ayuda en el desarrollo del sistema nervioso de los niños . Lo cual promueve un mejor crecimiento, reduce la hiperactividad y mejora la concentración.

Every chamber we sell is meticulously engineered with the highest quality standards. Our commitment to quality and safety ensures you receive a product you can rely on for years to come.

FAQs

What is Hyperbaric Oxygen Therapy (HBOT)?

HBOT is a medical treatment where a person breathes in 100% oxygen in a chamber with increased atmospheric pressure. The enhanced pressure allows more oxygen to reach the cells and tissues in the body, promoting healing and fighting infections.

How does HBOT work?

Under increased pressure within an HBOT chamber, oxygen is more readily absorbed into the bloodstream, body fluids, and tissues. This enhanced oxygen absorption promotes wound healing, reduces inflammation, and can even help combat certain types of infections.

What are the benefits of HBOT?

HBOT is known to accelerate the healing process in both chronic and acute conditions, reduce inflammation, aid in recovery from injuries, enhance the immune response, and improve the quality of sleep.

Is HBOT safe?

Yes, HBOT is considered a safe treatment. Side effects are rare and typically mild, such as ear discomfort due to pressure changes. Some people may need to ask their doctor, but HBOT is safe for most people.

What does a typical HBOT session look like?

A typical session lasts between 60 to 90 minutes, during which you lie or sit in a pressurized chamber, breathing in 100% oxygen. You can relax, sleep, or listen to music during the treatment.

How many HBOT sessions will I need?

The number of sessions depends on the condition being treated and how a person responds to the therapy. For some conditions, ongoing treatment may be needed.

Will I feel claustrophobic in an HBOT chamber?

The design of modern HBOT chambers minimizes feelings of claustrophobia. Most are spacious and equipped with windows, allowing natural light to enter.

Our clients can also communicate with the therapy operator throughout the session.

What should I wear during an HBOT session?

You should wear comfortable, loose-fitting clothing during your session. You can bring your phone, and catch up on that book you wanted to read; we even have others who love to come in and work on their laptop.

What should I charge clients for a session in the hyperbaric chamber?

Pricing can vary greatly depending on your location, the type of services you offer, and the length of the sessions. However, a typical range might be from $100 to $250 per session. Our recommendation is to offer

lower prices to keep the chamber running through the day, and maximizing the value to your clients. We have a very good understanding on how to best price HBOT services and how to create a membership program to produce recurring income.

Our wellness centers have created over 36 memberships in 7 months. Clients love the way they feel using HBOT and they become addicted (in a good way) to come in regularly.