Comprehensive HBOT Research: Exploring the Science
Behind Hyperbaric Oxygen Therapy
Discover the Latest Studies and Timeless Insights on the
Benefits of Hyperbaric Oxygen Therapy (HBOT)"
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Research Supporting Hyperbaric Oxygen Therapy (HBOT)
At HBOT Revolution, we are committed to providing the most comprehensive and up-to-date information on the benefits of Hyperbaric Oxygen Therapy (HBOT). Our curated database of studies highlights the diverse applications of HBOT, ranging from improving brain metabolism and treating cerebral palsy to addressing autoimmune inflammation and neurological recovery. While some of the studies on our website date back over 20 years, they continue to provide foundational insights into the mechanisms and efficacy of HBOT. As new research emerges, we are dedicated to updating this section to reflect the latest advancements in the field.
Whether you are exploring HBOT for its anti-inflammatory properties, neuroprotective benefits, or potential for enhancing recovery in conditions like cerebral palsy or stroke, this resource offers scientifically backed information to support your journey. Explore how HBOT is transforming health outcomes and discover how ongoing research continues to expand its applications.
Visit us often to stay informed about the newest studies and evidence in HBOT's revolutionary impact on wellness and recovery.
HBOT Mechanism
Bhutani S, Vishwanath G. "Hyperbaric oxygen and wound healing." Indian Journal of Plastic Surgery. 2012;45(2):316–324. doi:10.4103/0970-0358.101309. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490679/
Thom SR. "Hyperbaric oxygen: its mechanisms and efficacy." Plastic and Reconstructive Surgery. 2011;127(Suppl 1):131S–141S. doi:10.1097/PRS.0b013e3181fbe2bf.
Thom SR. "Oxidative stress is fundamental to hyperbaric oxygen therapy." Journal of Applied Physiology (1985). 2009;106(3):988–995. doi:10.1152/japplphysiol.91004.2008. Link: https://journals.physiology.org/doi/full/10.1152/japplphysiol.91004.2008
Wingelaar TT, Brinkman P, van Ooij PJAM, et al. "Markers of Pulmonary Oxygen Toxicity in Hyperbaric Oxygen Therapy Using Exhaled Breath Analysis." Frontiers in Physiology. 2019;10:475. Published 2019 Apr 24. doi:10.3389/fphys.2019.00475.
Link: https://www.frontiersin.org/articles/10.3389/fphys.2019.00475/fullGill
AL, Bell CNA. "Hyperbaric oxygen: its uses, mechanisms of action and outcomes." QJM: An International Journal of Medicine. 2004;97(7):385–395. doi:10.1093/qjmed/hch074.
Link: https://academic.oup.com/qjmed/article/97/7/385/1567601
HBOT and General Health
Fife CE, Eckert KA, Carter MJ. "An update on the appropriate role for hyperbaric oxygen: indications and evidence." Plastic and Reconstructive Surgery. 2016;138(3 Suppl):107S–116S. doi:10.1097/PRS.0000000000002714.
Thom SR. "Oxidative stress is fundamental to hyperbaric oxygen therapy." Journal of Applied Physiology (1985). 2009;106(3):988–995. doi:10.1152/japplphysiol.91004.2008.
Link: https://journals.physiology.org/doi/full/10.1152/japplphysiol.91004.2008
Fujita N, Ono M, Tomioka T, et al. "Effects of hyperbaric oxygen at 1.25 atmospheres absolute with normal air on macrophage number and infiltration during rat skeletal muscle regeneration." PLoS One. 2014;9(12). Published 2014 Dec 22. doi:10.1371/journal.pone.0115685.
Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115685
Vadas D, Kalichman L, Hadanny A, et al. "Hyperbaric oxygen environment can enhance brain activity and multitasking performance." Frontiers in Integrative Neuroscience. 2017;11:25. Published 2017 Sep 27. doi:10.3389/fnint.2017.00025.
Link: https://www.frontiersin.org/articles/10.3389/fnint.2017.00025/full
Hink J, Jansen E. "Are superoxide and/or hydrogen peroxide responsible for some of the beneficial effects of hyperbaric oxygen therapy?" Medical Hypotheses. 2001;57(6):764–769.
HBOT and Dementia/Alzheimer’s
Harch PG, Fogarty EF. "Hyperbaric oxygen therapy for Alzheimer’s dementia with positron emission tomography imaging: a case report." Medical Gas Research. 2019;8(4):181–184. Published 2019 Jan 9. doi:10.4103/2045-9912.248271.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347177/
Shapira R, Efrati S, Ashery U. "Hyperbaric oxygen therapy as a new approach for Alzheimer’s disease." Neural Regeneration Research. 2018;13(5):817–818. doi:10.4103/1673-5374.232475.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953028/
Qiang L, Lan X, Su-qin X, et al. "Meta-Analysis on the Efficacy and Safety of Hyperbaric Oxygen as Adjunctive Therapy for Vascular Dementia." Frontiers in Aging Neuroscience. 2019;11:86. doi:10.3389/fnagi.2019.00086.
Link: https://www.frontiersin.org/articles/10.3389/fnagi.2019.00086/full
HBOT and Fibromyalgia
Efrati S, Golan H, Bechor Y, et al. "Hyperbaric oxygen therapy can diminish fibromyalgia syndrome–prospective clinical trial." PLoS One. 2015;10(5). Published 2015 May 26. doi:10.1371/journal.pone.0127012.
Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127012
Hadanny A, Bechor Y, Catalogna M, et al. "Hyperbaric oxygen therapy can induce neuroplasticity and significant clinical improvement in patients suffering from fibromyalgia with a history of childhood sexual abuse–randomized controlled trial." Frontiers in Psychology. 2018;9:2495. doi:10.3389/fpsyg.2018.02495.
Link: https://www.frontiersin.org/articles/10.3389/fpsyg.2018.02495/full
Efrati S, Hadanny A, Daphna-Tekoah S, et al. "Recovery of repressed memories in fibromyalgia patients managed with hyperbaric oxygen–case series presentation and suggested bio-psycho-social mechanism." Frontiers in Psychology. 2018;9:848. doi:10.3389/fpsyg.2018.00848.
Link: https://www.frontiersin.org/articles/10.3389/fpsyg.2018.00848/full
Yildiz S, Kiralp MZ, Akin A, et al. "A new modality for fibromyalgia syndrome: hyperbaric oxygen therapy." Journal of International Medical Research. 2004;32(3):263-267.
Link: https://journals.sagepub.com/doi/10.1177/147323000403200313
HBOT and Autism
Rossignol DA, Bradstreet JJ, Van Dyke K, et al. "Hyperbaric oxygen in autism spectrum disorders." Medical Gas Research. 2012;2(1):16. doi:10.1186/2045-9912-2-16.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447607/
Rossignol DA, Rossignol LW, Smith S, et al. "Hyperbaric for children with autism: a multicenter, randomized, double-blind, controlled trial." BMC Pediatrics. 2009;9:21. doi:10.1186/1471-2431-9-21.
Link: https://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-9-21
Xiong T, Chen H, Luo R, et al. "Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD)." Cochrane Database of Systematic Reviews. 2016;10. doi:10.1002/14651858.CD010922.pub2.
Link: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010922.pub2/full
Rossignol DA, Rossignol LW. "Hyperbaric oxygen therapy may improve symptoms in autistic children." Medical Hypotheses. 2006;67(2):216-228. doi:10.1016/j.mehy.2006.02.009.
Link: https://www.sciencedirect.com/science/article/abs/pii/S0306987706001181
Rossignol DA, Frye RE. "Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism." Frontiers in Physiology. 2014;5:150. doi:10.3389/fphys.2014.00150.
Link: https://www.frontiersin.org/articles/10.3389/fphys.2014.00150/full
HBOT and Infection
Çimşit M, Uzun G, Yıldız S. "Hyperbaric oxygen therapy as an anti-infective agent." Expert Review of Anti-infective Therapy. 2009;7(8):1015-1026. doi:10.1586/eri.09.76.
Link: https://www.tandfonline.com/doi/full/10.1586/eri.09.76
Ezra N, Dang K, Heuser G. "Improvement of attention span and reaction time with hyperbaric oxygen in patients with toxic injury due to mold exposure." European Journal of Clinical Microbiology & Infectious Diseases. 2011;30(1):1–6. doi:10.1007/s10096-010-0937-8.
Link: https://link.springer.com/article/10.1007/s10096-010-0937-8
Mader JT, Brown GL, Guckian JC, et al. "A mechanism for the amelioration by hyperbaric oxygen of experimental staphylococcal osteomyelitis in rabbits." Journal of Infectious Diseases. 1980;142(6):915-922.Link: https://academic.oup.com/jid/article-abstract/142/6/915/2192487
Delasotta LA, Hanflik A, Bicking G, et al. "Hyperbaric oxygen for osteomyelitis in a compromised host." Open Orthopaedics Journal. 2013;7:114–117. doi:10.2174/1874325001307010114.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688397/
Ciofu O, Tolker-Nielsen T. "Tolerance and resistance of Pseudomonas aeruginosa biofilms to antimicrobial agents–how P. aeruginosa can escape antibiotics." Frontiers in Microbiology. 2019;10:913. doi:10.3389/fmicb.2019.00913.
Link: https://www.frontiersin.org/articles/10.3389/fmicb.2019.00913/full
Kolpen M, Lerche CJ, Kragh KN, et al. "Hyperbaric oxygen sensitizes anoxic pseudomonas aeruginosa biofilm to ciprofloxacin." Antimicrobial Agents and Chemotherapy. 2017;61(11). doi:10.1128/AAC.01024-17.
Link: https://journals.asm.org/doi/full/10.1128/AAC.01024-17
Gade PAV, Olsen TB, Jensen PØ, et al. "Modeling of ciprofloxacin killing enhanced by hyperbaric oxygen in Pseudomonas aeruginosa PAO1 biofilms." PLoS One. 2018;13(6). doi:10.1371/journal.pone.0198909.
Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198909
Memar MY, Yekani M, Alizadeh N, et al. "Hyperbaric oxygen therapy: antimicrobial mechanisms and clinical application for infections." Biomedicine & Pharmacotherapy. 2019;109:440-447. doi:10.1016/j.biopha.2018.10.142.
Link: https://www.sciencedirect.com/science/article/abs/pii/S0753332218310296
Kaye D. "Effect of hyperbaric oxygen on Clostridia in vitro and in vivo." Proceedings of the Society for Experimental Biology and Medicine. 1967;124:360.Link: https://journals.sagepub.com/doi/10.3181/00379727-124-31795
HBOT and Cancer (Including Keto)
İyikesici M, Slocum A, Slocum A, et al. "Efficacy of metabolically supported chemotherapy combined with ketogenic diet, hyperthermia, and hyperbaric oxygen therapy for stage IV triple-negative breast cancer." Cureus. 2017;9(7). doi:10.7759/cureus.1445.
Link: https://www.cureus.com/articles/7542
Poff AM, Ari C, Seyfried TN, et al. "The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer." PLoS One. 2013;8(6). doi:10.1371/journal.pone.0065522.Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065522
Seyfried TN, Mukherjee P. "The metabolic link between cancer and nutrition." Nutrition and Metabolism. 2005;2:30. doi:10.1186/1743-7075-2-30.Link: https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-2-30
Vander Heiden MG, Cantley LC, Thompson CB. "Understanding the Warburg effect: the metabolic requirements of cell proliferation." Science. 2009;324(5930):1029–1033. doi:10.1126/science.1160809.Link: https://www.science.org/doi/full/10.1126/science.1160809
Cancer (HBOT Only)
Moen I, Stuhr LE. "Hyperbaric oxygen therapy and cancer: a review." Target Oncology. 2012;7(4):233–242. doi:10.1007/s11523-012-0233-x.Link: https://link.springer.com/article/10.1007/s11523-012-0233-x
Thom SR, Bhopale VM, Yang M. "Microparticle-induced vascular injury in mice following decompression is inhibited by hyperbaric oxygen: effects on microparticles and interleukin-1." Journal of Applied Physiology. 2019;126(4):1093–1100.Link: https://journals.physiology.org/doi/full/10.1152/japplphysiol.00909.2018
Niezgoda JA, Serena TE, Carter MJ. "Outcomes of radiation injuries using hyperbaric oxygen therapy: an observational cohort study." Advances in Skin & Wound Care. 2016;29(1):12-19.Link: https://journals.lww.com/aswcjournal/Abstract/2016/01000/Outcomes_of_Radiation_Injuries_Using_Hyperbaric.5.aspx
Stepień K, Ostrowski RP, Matyja E. "Hyperbaric oxygen as an adjunctive therapy in the management of malignancies, including brain tumors." Medical Oncology. 2016;33(9):101. doi:10.1007/s12032-016-0814-0.Link: https://link.springer.com/article/10.1007/s12032-016-0814-0
Oscarsson N, Ny L, Mölne J, et al. "Hyperbaric oxygen reverses radiation-induced pro-fibrotic and oxidative stress responses in a rat model." Free Radical Biology and Medicine. 2017;103:248–255. doi:10.1016/j.freeradbiomed.2016.12.030.Link: https://www.sciencedirect.com/science/article/abs/pii/S0891584916311065
Zembrzuska K, Ostrowski RP, Matyja E. "Hyperbaric oxygen increases glioma cell sensitivity to antitumor drugs with a novel isothiourea derivative in vitro." Oncology Reports. 2019;41(5):2703–2716. doi:10.3892/or.2019.7064.Link: https://www.spandidos-publications.com/10.3892/or.2019.7064
Lu QZ, Li X, Ouyang J, et al. "Further application of hyperbaric oxygen in prostate cancer." Medical Gas Research. 2019;8(4):167–171. Published 2019 Jan 9. doi:10.4103/2045-9912.248268.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347175/
Choudhury R. "Hypoxia and hyperbaric oxygen therapy: a review." International Journal of General Medicine. 2018;11:431–442. Published 2018 Nov 20. doi:10.2147/IJGM.S172460.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248342/
HBOT and Wound Healing
Health Quality Ontario. "Hyperbaric oxygen therapy for the management of diabetic foot ulcers: a health technology assessment." Ontario Health Technology Assessment Series. 2017;17(5):1–142.Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461900/
Bhutani S, Vishwanath G. "Hyperbaric oxygen and wound healing." Indian Journal of Plastic Surgery. 2012;45(2):316–324. doi:10.4103/0970-0358.101309. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490679/
Hou S, Wu G, Liang J, et al. "Hyperbaric oxygen on rehabilitation of brain tumors after surgery and effects on TNF-α and IL-6 levels." Oncology Letters. 2019;17(3):3277–3282. doi:10.3892/ol.2019.10000.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394675/
Perren S, Gatt A, Papanas N, et al. "Hyperbaric oxygen therapy in ischemic foot ulcers in type 2 diabetes: a clinical trial." Open Cardiovascular Medicine Journal. 2018;12:80–85. Published 2018 Aug 31. doi:10.2174/1874192401812010080.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135494/
Eskes AM, Ubbink DT, Lubbers MJ, et al. "Hyperbaric oxygen therapy: solution for difficult-to-heal acute wounds? Systematic review." World Journal of Surgery. 2011;35(3):535–542. doi:10.1007/s00268-010-0923-4.
Link: https://link.springer.com/article/10.1007/s00268-010-0923-4
HBOT and TBI/Concussion
Boussi-Gross R, Golan H, Fishlev G, et al. "Hyperbaric oxygen therapy can improve post-concussion syndrome years after mild traumatic brain injury – randomized prospective trial." PLoS One. 2013;8(11):e79995. Published 2013 Nov 15. doi:10.1371/journal.pone.0079995.
Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079995
Tal S, Hadanny A, Sasson E, et al. "Hyperbaric oxygen therapy can induce angiogenesis and regeneration of nerve fibers in traumatic brain injury patients." Frontiers in Human Neuroscience. 2017;11:508. Published 2017 Oct 19. doi:10.3389/fnhum.2017.00508.
Link: https://www.frontiersin.org/articles/10.3389/fnhum.2017.00508/full
Meng XE, Zhang Y, Li N, et al. "Hyperbaric oxygen alleviates secondary brain injury after trauma through inhibition of TLR4/NF-κB signaling pathway." Medical Science Monitor. 2016;22:284–288. Published 2016 Jan 26. doi:10.12659/msm.894148.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730336/
Vlodavsky E, Palzur M, Feinsod M, et al. "Evaluation of the apoptosis-related proteins of the BCL-2 family in the traumatic penumbra area of the rat model of cerebral contusion, managed by hyperbaric oxygen therapy: a quantitative immunohistochemical study." Acta Neuropathologica. 2005;110(2):120-126.
Link: https://link.springer.com/article/10.1007/s00401-005-1054-8
Hadanny A, Abbott S, Suzin G, et al. "Effect of hyperbaric oxygen therapy on chronic neurocognitive deficits of post-traumatic brain injury patients: retrospective analysis." BMJ Open. 2018;8(9):e023387. Published 2018 Sep 28. doi:10.1136/bmjopen-2018-023387.
Link: https://bmjopen.bmj.com/content/8/9/e023387
Dong Y, Hu XH, Wu T, et al. "Effect of hyperbaric oxygenation therapy on post-concussion syndrome." Experimental and Therapeutic Medicine. 2018;16(3):2193–2202. doi:10.3892/etm.2018.6463.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112572/
Tsutsumi I, Tsujimoto Y, Takahashi S, et al. "Hyperbaric oxygen therapy for persistent post-concussion syndrome following mild traumatic brain injury." Cochrane Database of Systematic Reviews. 2017;2017(7):CD012727. doi:10.1002/14651858.CD012727.
Link: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012727/full
Eve DJ, Steele MR, Sanberg PR, et al. "Hyperbaric oxygen therapy as a potential treatment for post-traumatic stress disorder associated with traumatic brain injury." Neuropsychiatric Disease and Treatment. 2016;12:2689–2705. doi:10.2147/NDT.S110126.
HBOT and Stroke Recovery
Rosario ER, Kaplan SE, Khonsari S, et al. "The effect of hyperbaric oxygen therapy on functional impairments caused by ischemic stroke." Neurology Research International. 2018;2018:3172679. doi:10.1155/2018/3172679.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192086/
Ostrowski RP, Stepien K, Pucko E, et al. "The efficacy of hyperbaric oxygen in hemorrhagic stroke: experimental and clinical implications." Archives of Medical Science. 2017;13(5):1217–1223. doi:10.5114/aoms.2017.65081.
Efrati S, Fishlev G, Bechor Y, et al. "Hyperbaric oxygen induces late neuroplasticity in post-stroke patients–randomized, prospective trial." PLoS One. 2013;8(1):e53716. doi:10.1371/journal.pone.0053716.
Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053716
Liska GM, Lippert T, Russo E, et al. "A dual role for hyperbaric oxygen in stroke neuroprotection: preconditioning of the brain and stem cells." Conditioning Medicine. 2018;1(4):151–166.
Hadanny A, Efrati S. "Oxygen–a limiting factor for brain recovery." Critical Care. 2015;19(1):307. doi:10.1186/s13054-015-1034-2.
Link: https://ccforum.biomedcentral.com/articles/10.1186/s13054-015-1034-2
Hadanny A, Golan H, Fishlev G, et al. "Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage." Restorative Neurology and Neuroscience. 2015;33(4):471–486. doi:10.3233/RNN-150517.
Link: https://content.iospress.com/articles/restorative-neurology-and-neuroscience/rnn150517
HBOT for PTSD
Eve DJ, Steele MR, Sanberg PR, et al. "Hyperbaric oxygen therapy as a potential treatment for post-traumatic stress disorder associated with traumatic brain injury." Neuropsychiatric Disease and Treatment. 2016;12:2689–2705. doi:10.2147/NDT.S110126.
Harch PG, Andrews SR, Fogarty EF, et al. "Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder." Medical Gas Research. 2017;7(3):156–174. doi:10.4103/2045-9912.215745.
He H, Li X, He Y. "Hyperbaric oxygen therapy attenuates neuronal apoptosis induced by traumatic brain injury via Akt/GSK3β/β-catenin pathway." Neuropsychiatric Disease and Treatment. 2019;15:369–374. doi:10.2147/NDT.S183632.
HBOT and Other Neurological Issues
Nazario J, Kuffler DP. "Hyperbaric oxygen therapy and promoting neurological recovery following nerve trauma." Undersea and Hyperbaric Medicine. 2011;38(5):345–366.
Link: https://www.uhms.org/publications/journals/undersea-and-hyperbaric-medicine.html
Hu Q, Manaenko A, Xu T, et al. "Hyperbaric oxygen therapy for traumatic brain injury: bench-to-bedside." Medical Gas Research. 2016;6(2):102–110. Published 2016 Jul 11. doi:10.4103/2045-9912.184720.
Taghizadeh Asl M, Nemati R, Chabi N, et al. "Brain perfusion imaging with voxel-based analysis in secondary progressive multiple sclerosis patients with a moderate to severe stage of disease: a boon for the workforce." BMC Neurology. 2016;16:79. doi:10.1186/s12883-016-0605-4.
Link: https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-016-0605-4
Kiralp MZ, Yildiz Ş, Vural D, et al. "Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome." Journal of International Medical Research. 2004;32(3):258–262.
Link: https://journals.sagepub.com/doi/10.1177/147323000403200309
Oroglu B, Turker T, Aktas S, et al. "Effect of hyperbaric oxygen therapy on tensile repair of the peripheral nerves." Undersea and Hyperbaric Medicine. 2011;38(5):367–373.
Link: https://www.uhms.org/publications/journals/undersea-and-hyperbaric-medicine.html
Vadas D, Kalichman L, Hadanny A, et al. "Hyperbaric oxygen environment can enhance brain activity and multitasking performance." Frontiers in Integrative Neuroscience. 2017;11:25. doi:10.3389/fnint.2017.00025.
Link: https://www.frontiersin.org/articles/10.3389/fnint.2017.00025/full
Hadanny A, Maliar A, Fishlev G, et al. "Reversibility of retinal ischemia due to central retinal artery occlusion by hyperbaric oxygen." Clinical Ophthalmology. 2016;11:115–125. doi:10.2147/OPTH.S121307.
HBOT and Pain-Inflammation
Meng XE, Zhang Y, Li N, et al. "Hyperbaric oxygen alleviates secondary brain injury after trauma through inhibition of TLR4/NF-κB signaling pathway." Medical Science Monitor. 2016;22:284–288. doi:10.12659/msm.894148.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730336/Dulai PS, Gleeson MW, Taylor D, et al. "Systematic review: the safety and efficacy of hyperbaric oxygen therapy for inflammatory bowel disease." Alimentary Pharmacology & Therapeutics. 2014;39(12):1266–1275. doi:10.1111/apt.12753.
Link: https://onlinelibrary.wiley.com/doi/10.1111/apt.12753Hui J, Zhang ZJ, Zhang X, et al. "Repetitive hyperbaric oxygen treatment attenuates complete Freund’s adjuvant-induced pain and reduces glia-mediated neuroinflammation in the spinal cord." Journal of Pain. 2013;14(7):747–758.
Link: https://pubmed.ncbi.nlm.nih.gov/23528604/Li F, Fang L, Huang S, et al. "Hyperbaric oxygenation therapy alleviates chronic constrictive injury-induced neuropathic pain and reduces tumor necrosis factor-alpha production." Anesthesia & Analgesia. 2011;113(3):626–633.
Link: https://journals.lww.com/anesthesia-analgesia/Abstract/2011/09000/Hyperbaric_Oxygenation_Therapy_Alleviates_Chronic.25.aspxChoudhury R. "Hypoxia and hyperbaric oxygen therapy: a review." International Journal of General Medicine. 2018;11:431–442. doi:10.2147/IJGM.S172460.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248342/
HBOT and Mitochondria
Palzur E, Zaaroor M, Vlodavsky E, et al. "Neuroprotective effect of hyperbaric oxygen therapy in brain injury is mediated by preservation of mitochondrial membrane properties." Brain Research. 2008;1221:126–133. doi:10.1016/j.brainres.2008.05.051.
Link: https://www.sciencedirect.com/science/article/abs/pii/S000689930800910XDave KR, Prado R, Busto R, et al. "Hyperbaric oxygen therapy protects against mitochondrial dysfunction and delays onset of motor neuron disease in wobbler mice." Neuroscience. 2003;120(1):113–120. doi:10.1016/S0306-4522(03)00244-6.
Link: https://www.sciencedirect.com/science/article/abs/pii/S0306452203002446Meyer JN, Hartman JH, Mello DF. "Mitochondrial toxicity." Toxicological Sciences. 2018;162(1):15–23. doi:10.1093/toxsci/kfx236.
Link: https://academic.oup.com/toxsci/article/162/1/15/4818606Meyer JN, Leung MC, Rooney JP, et al. "Mitochondria as a target of environmental toxicants." Toxicological Sciences. 2013;134(1):1–17. doi:10.1093/toxsci/kft102.
Link: https://academic.oup.com/toxsci/article/134/1/1/1663430
HBOT and Microbiome
Schmidt TM, Kao JY. "A little O2 may go a long way in structuring the GI microbiome." Gastroenterology. 2014;147(5):956–959. doi:10.1053/j.gastro.2014.09.025.
Link: https://www.gastrojournal.org/article/S0016-5085(14)01135-0/fulltextNyabanga CT, Kulkarni G, Shen B. "Hyperbaric oxygen therapy for chronic antibiotic-refractory ischemic pouchitis." Gastroenterology Report. 2017;5(4):320–321. doi:10.1093/gastro/gov038.
Link: https://academic.oup.com/gastro/article/5/4/320/3073986Albenberg L, Esipova TV, Judge CP, et al. "Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota." Gastroenterology. 2014;147(5):1055–1063.e8. doi:10.1053/j.gastro.2014.07.020.
Link: https://www.gastrojournal.org/article/S0016-5085(14)00890-3/fulltextCrabbé A, Jensen PO, Bjarnsholt T, et al. "Antimicrobial tolerance and metabolic adaptations in microbial biofilms." Trends in Microbiology. 2019;27(10):850–863. doi:10.1016/j.tim.2019.05.003.
Link: https://www.cell.com/trends/microbiology/fulltext/S0966-842X(19)30120-3
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The Science Behind
Hyperbaric Therapy
The Science Behind
Hyperbaric Therapy
Why Should You Consider Hyperbaric Oxygen Therapy?
Hyperbaric Oxygen Therapy (HBOT) represents an advanced, evidence-backed treatment modality that can significantly enhance the service offerings in your practice.
For those on the cutting edge of wellness, embracing biohacking practices and the pursuit of optimal health, Hyperbaric Oxygen Therapy (HBOT) offers a scientifically grounded and potent modality to consider. Incorporating HBOT into your biohacking regimen can elevate your health optimization strategies and unlock new wellness potential.
Being non-invasive and having extensive support for its effectiveness, HBOT is an appealing addition for any health-focused individual.
Value-Driven, Portable Hyperbaric Chambers
We have revolutionized the wellness field with our pioneering approach to hyperbaric therapy. From our earliest days, our commitment has been to deliver exceptionally safe, high-quality, and conveniently portable hyperbaric chambers to physicians, elite athletes, wellness centers, and families.
Our chambers empower users with the ability to self-administer treatment, ushering in a new era of hyperbaric technology.
We've thoughtfully designed our portable range to offer not just simplicity and convenience, but also the best value for your investment. These cost-effective chambers provide impactful therapy that has benefited hundreds of thousands of people globally.
You're investing in a product that combines affordability with top-tier therapeutic technology.
Best Hyperbaric Oxygen Therapy Chambers (HBOT)
Experience
Nuestro primer objetivo es ayudarlo a aliviar su dolor e incomodidad lo antes posible.
Safety
Our chambers are the preferred choice for an increasing number of doctors, elite athletes, and households for their recovery needs. Our confidence stems from our commitment to ensuring each chamber we distribute achieves the industry's top safety ratings.
Customer Support
El cuidado ayuda en el desarrollo del sistema nervioso de los niños . Lo cual promueve un mejor crecimiento, reduce la hiperactividad y mejora la concentración.
Every chamber we sell is meticulously engineered with the highest quality standards. Our commitment to quality and safety ensures you receive a product you can rely on for years to come.
FAQs
What are multiplace hyperbaric chambers?
Multiplace hyperbaric chambers are designed to accommodate multiple users simultaneously, offering flexibility for facilities catering to individuals, small groups, or families.
What capacities are available for multiplace chambers?
Multiplace chambers come in configurations for 2, 3, or 4 users, providing options to meet the unique needs of wellness centers, athletic facilities, and other organizations.
What is the pressure range for these chambers?
These chambers offer an adjustable pressure range, typically from 1.3 ATA to 2.0 ATA, making them versatile for a variety of wellness and recovery-focused hyperbaric oxygen therapy protocols.
What are the benefits of adjustable pressure levels?
Lower pressures (1.3–1.6 ATA) are ideal for general wellness and relaxation, while higher pressures (1.8–2.0 ATA) are suited for more focused recovery and performance enhancement.
How do multiplace chambers support wellness and recovery?
Regular use can help improve energy levels, enhance recovery, reduce inflammation, and promote overall wellness, making these chambers a valuable addition to any wellness-focused facility.
Are multiplace chambers safe to use?
Yes, multiplace chambers are built with safety in mind, featuring durable construction, pressure monitoring systems, emergency release mechanisms, and clear communication tools for user confidence.
What are the advantages of a walk-in design?
Walk-in chambers provide easy accessibility, especially for individuals with mobility challenges, and create a spacious, comfortable environment for therapy sessions.
Can the chambers be customized for different users?
Yes, with adjustable pressure settings and the ability to accommodate 1 to 4 users, these chambers are highly flexible to suit various needs and treatment goals.
Where can I buy a multiplace hyperbaric chamber or talk to someone for guidance?
You can call or text George at [714] 786-3831. George is the owner of three wellness centers under the HBOT Planet brand and has extensive experience in hyperbaric oxygen therapy. He can personally guide you in making the right purchase based on your specific needs.
Copyright © 2025 HBOT Revolution USA, All rights reserved. | In Association with HBOT Planet & Oxygen Health System
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